Abstract

Experimental Models of Early Exposure to Alcohol: A Way to Unravel the Neurobiology of Mental Retardation

Highlights

  • As of November 2014, a PubMed search for“fetal alcohol”retrieved more than 14,500 articles

  • We are grateful to Marina Guizzetti and her coworkers, who shed light on how glial cells guide neural development and how this pivotal function can be disrupted during fetal alcohol spectrum disorders (FASD) (5)

  • There is no doubt that the cerebral cortex is one of the key structures affected by early exposure to alcohol and its impairment is responsible for most of the cognitive defects observed in FASD

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Summary

Introduction

As of November 2014, a PubMed search for“fetal alcohol”retrieved more than 14,500 articles. In the present Research Topic, hosted by Frontiers in Pediatrics, we have gathered some of the most outstanding scientists, among those actively involved in the experimental study of FASD. The review article by Brian Christie and coworkers provides a useful guide for the experimental neurobiologist, highlighting pros and cons of the most widely used animal models of FASD (2).

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