Experimental Investigation on Thermal Conductivity and Thermal Diffusivity of Ex-Vivo Bovine Liver from Room Temperature down to -60 °C.

Abstract

Ex vivo animal tissues (e.g., bovine liver) as well as water-agar gel are commonly used to simulate both experimentally and numerically the response of human tissues to cryoablation treatments. Data on the low temperature thermal properties of bovine liver are difficult to find in the literature and very often are not provided for the whole temperature range of interest. This article presents the thermal conductivity and thermal diffusivity measurements performed on ex-vivo bovine liver samples using the transient plane source method. Regression coefficients are provided to determine these properties in different temperature ranges except for the phase transition during which no results were obtained, which suggests an ad hoc calorimetric analysis. A quick procedure is also suggested to determine the water mass fraction in the tissue. Moreover, an attempt to estimate the liver density in the frozen state using measurements performed solely at room temperature is also presented. The measured thermal conductivity and thermal diffusivity values are compared with data reported in literature highlighting a spread up to 40%. Moreover, it emerges that water-agar gel usually made with 2% by weight of agar does not show the same thermal properties as the bovine liver.