Abstract

Currently little is known about the role of the various constituents of the biliary pole of the hepatocyte in the process of cholestasis. In an attempt to delineate their respective roles we used three approaches-physiopathology, ultrastructure and cytochemistry- to study three types of chemically induced intrahepatic cholestasis: sodium taurolithocholate (NaTL-)cholestasis, phalloidin (P-)cholestasis, and cholestasis caused by the successive action of these two agents (mixed cholestasis).

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