Abstract
Little is known about the relationships between Rickettsia conorii conorii, the agent of Mediterranean spotted fever (MSF), and its main vector, the brown dog tick Rhipicephalus sanguineus [1]. Matsumoto et al. recently reported a high mortality of Rh. sanguineus group ticks infected with R. conorii conorii by several methods including the use of a bacteraemic rabbit [2]. It had been speculated that reasons for this reduction in fitness might include the geographic origin of the ticks, which came from Thailand where R. conorii conorii has not been reported, or was associated with the pathogen load acquired during laboratory experiments. Here we present complementary experiments to test these hypotheses.
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