Abstract

Bagaza virus (BAGV; synonymous to Israel turkey meningoencephalomyelitis virus, ITV) is a relevant arthropod-borne epornitic flavivirus. In its first emergence in Europe (southern Spain, 2010) BAGV caused an outbreak, severely affecting red-legged partridges and common pheasants. The effects (pathogenicity, role as reservoir host) of BAGV in other European phasianids are unknown. To fill this gap, grey partridges were experimentally infected with BAGV. The clinical course of the disease was severe, with neurological signs, significant weight loss and 40% mortality. Low viral loads in the blood and the absence of contact transmission suggest a limited—if any—role on BAGV transmission for this European phasianid.

Highlights

  • Bagaza virus (BAGV; synonymous to Israel turkey meningoencephalomyelitis virus, ITV) is a relevant arthropod-borne epornitic flavivirus

  • Introduction, methods and results Bagaza virus (BAGV), synonymous to Israel turkey meningoencephalomyelitis virus (ITV), is a mosquitoborne epornitic virus belonging to the Ntaya serocomplex within the Flavivirus genus of the family Flaviviridae

  • BAGV/ITV was restricted to sub-Saharan Africa (Central African Republic, Mauritania, Senegal and South Africa), Israel and India [5,6,7,8], but in 2010 it emerged for the first time in Europe causing an outbreak

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Summary

Open Access

Experimental infection of grey partridges with Bagaza virus: pathogenicity evaluation and potential role as a competent host. Cristina Cano‐Gómez1* , Francisco Llorente, Elisa Pérez‐Ramírez, Ramón C.

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Discussion
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Necropsy group

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