Abstract

When the titre of pantropic RVF virus was estimated in cattle, the results compared favourably with those obtained in adult mice and tissue cultures. The intensity of response to experimental infection did not depend on the amount of virus inoculated. The response of individual cattle to experimental injection varied considerably when judged by pyrexia, viraemia and circulating neutralizing antibody. The susceptibility of cattle could not be judged solely by the absence of neutralizing antibody in their pre-challenge sera, as assessed by the serum-virus neutralization test carried out in adult mice.

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