Abstract
s1 May 1961Experimental Induction of Iso-Immune Hemolytic Anemia in Man by Transfusion of Unusually Potent Anti-Rh Antibodies.H. S. Bowman, M.D., F.A.C.P., J. F. Mohn, M.D., R. M. Lambert, F. W. Brason, M.D.H. S. Bowman, M.D., F.A.C.P.Search for more papers by this author, J. F. Mohn, M.D.Search for more papers by this author, R. M. LambertSearch for more papers by this author, F. W. Brason, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-54-5-1061_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn an earlier study of experimental transfusion of donor plasma containing blood group antibodies into incompatible normal human recipients, a single ACD plasma containing exceptional anti-CD antibodies induced iso-immune hemolytic anemia in a CwDe/Ce (R1wR1) volunteer. The hematologic and immunologic observations made closely paralleled those found in naturally-occurring warm-antibody type acquired hemolytic anemia, and indicated that further detailed studies on additional recipients transfused with this unique anti-CD plasma might provide some insight into the pathogenesis of the spontaneously-occurring disorder.The equivalent of a single unit of plasma of a sterile pool of three bleedings from the same donor was transfused... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1961Volume 54, Issue 5Page: 1061-1061KeywordsAntibodiesBlood donorsBlood groupsBlood plasmaHemolytic anemiaHemorrhagePathogenesis Issue Published: 1 May 1961 PDF downloadLoading ...
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