Abstract
SummaryThe owl monkey, Aotus trivir-gatus, was found to be extremely susceptible to infection with a strain of Herpesvirus hominis. The infection was established by ocular inoculation without corneal scarification, rapidly involved the upper respiratory tract, blood, and became widespread, systemically. Generally animals died within a period of 6 days after inoculation and virus was recovered from all organs and the CNS. Exposure of well to sick animals resulted in similar generalized disease and death in a majority of those exposed. The pathology of generalized infection closely resembled H. hominis infection of the human new born infant.
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