Abstract
SUMMARY A first report is made of the effects of duck hepatitis virus (DHV) in mallards. Day-old mallard ducklings exposed to DHV by five different routes developed clinical disease. As in domestic Pekins, adult mallards were refractory to DHV. Ducklings that died from DHV were in a typical opisthotonic posture. The principal lesions detected at necropsy were a greatly swollen, enlarged, hemorrhagic liver and an enlarged spleen. Histologically, the earliest prominent liver lesions were an infiltration of chronic inflammatory cells and proliferation of bile duct epithelium, followed by hemorrhage and extensive necrosis of hepatic cells. A viremia was detected as early as 10 hr postinoculation (PI) in 10day-old mallard ducklings inoculated intraperitoneally (IP), peaked at 30 hr PI, and was diminishing by 92 hr PI.
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