Abstract
The pathogenic potential of deerpox virus was investigated via an experimental study utilizing seven black-tailed deer fawns (Odocoileus hemionus) between June and August of 2007. Successful transmission was achieved via intracutaneous and intravenous routes, and by commingling an uninoculated animal with experimentally infected fawns. One fawn became depressed and reluctant to eat but systemic clinical signs in the other fawns were confined to mild transient pyrexia. Typical multifocal poxviral cutaneous lesions of erythema, papules, pustules, ulceration, and crusting were observed. Two locally extensive ulcerative lesions also developed at inoculation sites. Oral lesions were seen in one commingled fawn, with some palatine epithelial cells containing intracytoplasmic inclusions. Microscopic cutaneous lesions included epithelial cell hyperplasia with hydropic change, intraepithelial pustules, erosions, folliculitis, and dense leukocytic dermal infiltrates. Transmission was confirmed by one or more of virus isolation, polymerase chain reaction or serum neutralization tests. Significant internal lesions were not seen at necropsy.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
