Abstract

The experimental arrangements used for external beam PIXE analysis of biomedical samples are surveyed. Emphasis is given to the instrumental and physical aspects of the various measuring systems. Special features of the setups and other means of obtaining optimal measuring conditions play an important role in many cases. The proper choice of bombarding proton energy and the minimization of the system background radiation make significant contributions to the sensitivity obtainable by the technique. Parameters such as exit foil materials, setup cons- truction materials, gas atmosphere used (eg. He, air), beam current normalization and system geometry are of specific interest. Some typical recent examples in the field are given.

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