Experimental and predicted solubilities of 3,4-dichlorobenzoic acid in select organic solvents and in binary aqueous–ethanol mixtures

Abstract

Experimental solubilities are reported for 3,4-dichlorobenzoic acid dissolved in methyl butyrate, and in 16 alcohol, 5 alkyl acetate, 5 alkoxyalcohol and 6 ether solvents. Solubilities were also measured in nine binary aqueous–ethanol solvent mixtures at 298.15 K. The measured solubility data were correlated with the Abraham solvation parameter model. Mathematical expressions based on the Abraham model predicted the observed molar solubilities to within 0.12 log units.