Abstract
Experiences and Lessons from a Multicountry NIDIAG Study on Persistent Digestive Disorders in the Tropics.
Highlights
Persistent digestive disorders can be defined as any diarrhea lasting for at least two weeks and/or abdominal pain that persists for two weeks or longer [1,2,3]
As the Neglected Infectious diseases DIAGnosis (NIDIAG) project draws to an end, we feel that experiences and lessons learnt must be shared with the broader research community, clinicians, and disease control managers in countries where digestive disorders due to neglected tropical diseases (NTDs) remain an important public health issue (Box 1)
There is a need for studies investigating the etiology, diagnosis, and management of common clinical syndromes such as persistent digestive disorders in the tropics
Summary
Persistent digestive disorders can be defined as any diarrhea (i.e., three or more loose stools per day) lasting for at least two weeks and/or abdominal pain that persists for two weeks or longer [1,2,3]. With regard to the study on persistent digestive disorders, the main aims are (i) to identify the most important NTDs and other infectious agents that give rise to this clinical syndrome, including their relative frequency; (ii) to assess and compare the accuracy of different diagnostic methods; and (iii) to determine clinical responses to commonly employed empiric treatment options for persistent digestive disorders [9]. To this end, a case–control study has been implemented in four countries: Côte d’Ivoire and Mali in West Africa and Indonesia and Nepal in Asia. They provided the basis on which quality control activities could be performed
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