Experience with infections in the use of extracorporeal membrane oxygenation

Abstract

Abstract Objective To identify risk factors associated with infectious complications acquired by paediatric patients during extracorporeal life support (ECLS). Patients and methods Patients under ECLS from January 2011 to December 2014 have been retrospectively reviewed and data on demographics, care and infectious complications were collected. Results There were 50 ECLS assistances in the study period, of which 20 patients had 23 infectious complications: 16 were bloodstream infections, with coagulase negative staphylococci being the predominant isolate (there were 2 cases of candidaemia). Age, site of cannulation procedure, cannulation site, severe coagulopathy, and surgical interventions during assistance were analysed as risk factors for infectious complications, but no significant differences were found. ECLS duration was significantly longer in patients with infectious complications (8.91 vs 5.91 days; P = .039). There were no significant differences as regards Paediatric Intensive Care Unit (PICU) stay, or in survival. Conclusions Infectious complications during ECLS are very common, and ECLS duration is significantly longer in patients with infections. Measures should be put in place to prevent infectious complications and reduce time on ECLS.