Abstract
The use of ergotamine tartrate for the treatment of migraine headaches was first reported in 1926 by Maier.<sup>1</sup>Since then, a number of articles have appeared recording the results of treatment in single or in small groups of patients. The only large group is that of Tzanck,<sup>2</sup>who treated 101 patients with favorable results in a large but unstated percentage. A year ago, one of us (W. G. L.<sup>3</sup>) reviewed the literature and reported the results of parenteral injection in forty-five patients. Additional reports of treatment have appeared as follows: seven patients helped by oral administration (Podolsky<sup>4</sup>), headaches aborted by subcutaneous injection in fourteen of eighteen patients (Brock, O'Sullivan and Young<sup>5</sup>), and in each of nine patients (Logan and Allen<sup>6</sup>). Though the cases reported (including this series) number only 300, the dozen authors who have written on the subject are unanimous that the administration
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