Experience with bilateral renal artery stenosis as a cause of hypertension in childhood

Abstract

Since 1981, eight children have been treated at this hospital for hypertension due to bilateral renal artery stenosis (RAS). Useful diagnostic studies were DTPA renal scan following pretreatment with captopril, and selective renal angiography. All patients underwent attempted surgical revascularization of the RAS and three had aortoaortic bypass of an abdominal aortic narrowing. Of the 14 kidneys that had repair of RAS, a successful outcome was obtained in 11 (80%). Three patients required unilateral nephrectomy. Five of eight patients are normotensive and off all medications, and three are normotensive on reduced medication doses.