Abstract

Experience with a single dose of recombinant activated factor VII for the management of mild-to-moderate bleeds in haemophilia

Highlights

  • Experience with a single dose of recombinant activated factor VII for the management of mild-to-moderate bleeds in haemophilia

  • A single dose of rFVIIa 180 lg kg)1 stopped mild-to-moderate bleeding in 59% of bleeding episodes in children

  • Haemostasis was achieved after a second dose of 90 lg kg)1 rFVIIa in a further 37% of bleeding episodes

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Summary

Introduction

Experience with a single dose of recombinant activated factor VII for the management of mild-to-moderate bleeds in haemophilia Recombinant activated factor VII (rFVIIa; NovoSevenÒ, Novo Nordisk, Bagsværd, Denmark) is considered the first-line treatment option for controlling bleeding in haemophilia patients with inhibitors [2].

Results
Conclusion
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