Experience of the prophylactic use of penicillin in surgical practice

Abstract

Antibiotics have proven to be one of the most effective therapeutic and prophylactic agents in the last decade, of which penicillin has found the widest use in surgery to prevent infection after wounds and surgical interventions. Under our supervision there were 120 patients to whom penicillin was used for prophylactic purposes, in the absolute majority of cases in the postoperative period. Penicillin was injected into the abdominal cavity during the operation, 200,000-300,000 units, after the operation for 4 days, 200,000 units through a drainage tube, intramuscularly, 300,000 units. per day; sometimes penicillin was used in combination, that is, it was injected into the abdominal or pleural cavity, the edges of the wound were infiltrated and at the same time penicillin was injected intramuscularly.