Abstract

Recently double cancer has been increasingly found with a progress of diagnostic technique for cancers. This study focused on primary liver cell carcinoma to investigate double cancer of the liver and the other organ. In 207 cases of primary liver cell carcinoma experienced at the department during a recent one decade, there were 6 cases of double cancer arising in the liver and other organ. There were 3 males and 3 females, with an average age of 69 years. All 6 patients had synchronous double cancer, and other than liver cell carcinoma they were associated with early gastric cancer in 4, lung cancer in one, and colonic cancer in one. Operative procedures for liver cell carcinomas included left lobectomy in one, partial hepatectomy in 2, excision of the tumor in one, and hepatic artery insertion in one. Simultaneous excision of both cancers could be done in only one case undergoing gastrectomy for early gastric cancer. Each one case of early gastric and lung cancer underwent excision by two-step approach. Average prognosis was 11 months. Except for one patient surviving for 28 months after operation, remaining 5 patients died of liver cell carcinoma or hepatic failure. It may be concluded that prognosis of synchronous double cancer of the liver and other organ is prescribed by that of primary hepatic cancer.

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