Abstract
There are many cases of primary liver cancer associated with cirrhosis, presenting problems from the viewpoint of treatment. In our department, 72.7% of 157 patients with primary liver cancer had complicating cirrhosis. Among these 157 cases, hepatectomy was performed in 40 cases, intubation in the hepatic artery in 14, trans-arterial embolization of the hepatic artery by catheter (TAE) in 24, single laparotomy in 12, other forms of surgery in 7, chemotherapy in 35 and no treatment in 25. Mortality due to surgery after hepatectomy was 15%, and the final results for two-year and five-year accumulated survival rates were 38.0% and 30.4%, respectively, showing obviously good results as compared with the other treated groups. TAE was the most effective modality among cases in which it was impossible to perform excision. Factors related to the prognosis after hepatectomy were hemorrhage volume during surgery, operation time, ICGmax, KICG, albumin, S-GOT, S-GPT, glucagon, the rate of increase in blood cyclic AMP after loading, response form of OGTT and hepaplastin test. Thus, it is thought necessary to pay full attention to these factors both preopeartively and during surgery.
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