Abstract

BackgroundThe National Cervical Screening Program in Australia currently recommends that women aged 18–69 years are screened with conventional cytology every 2 years. Publicly funded HPV vaccination was introduced in 2007, and partly as a consequence, a renewal of the screening program that includes a review of screening recommendations has recently been announced. This study aimed to provide a baseline for such a review by quantifying screening program resource utilisation and costs in 2010.MethodsA detailed model of current cervical screening practice in Australia was constructed and we used data from the Victorian Cervical Cytology Registry to model age-specific compliance with screening and follow-up. We applied model-derived rate estimates to the 2010 Australian female population to calculate costs and numbers of colposcopies, biopsies, treatments for precancer and cervical cancers in that year, assuming that the numbers of these procedures were not yet substantially impacted by vaccination.ResultsThe total cost of the screening program in 2010 (excluding administrative program overheads) was estimated to be A$194.8M. We estimated that a total of 1.7 million primary screening smears costing $96.7M were conducted, a further 188,900 smears costing $10.9M were conducted to follow-up low grade abnormalities, 70,900 colposcopy and 34,100 histological evaluations together costing $21.2M were conducted, and about 18,900 treatments for precancerous lesions were performed (including retreatments), associated with a cost of $45.5M for treatment and post-treatment follow-up. We also estimated that $20.5M was spent on work-up and treatment for approximately 761 women diagnosed with invasive cervical cancer. Overall, an estimated $23 was spent in 2010 for each adult woman in Australia on cervical screening program-related activities.ConclusionsApproximately half of the total cost of the screening program is spent on delivery of primary screening tests; but the introduction of HPV vaccination, new technologies, increasing the interval and changing the age range of screening is expected to have a substantial impact on this expenditure, as well as having some impact on follow-up and management costs. These estimates provide a benchmark for future assessment of the impact of changes to screening program recommendations to the costs of cervical screening in Australia.

Highlights

  • The National Cervical Screening Program in Australia currently recommends that women aged 18–69 years are screened with conventional cytology every 2 years

  • Screening histories for women who participate in the cervical screening program are collected by State and Territory level Pap test registers [1,2] and the collected data are collated by the Australia Institute of Health and Welfare (AIHW) to produce annual public reports summarising participation rates in the program, early re-screening rates, abnormalities detected by cytology and histology, cervical cancer incidence and cervical cancer mortality in Australia

  • We estimate that there were 84,600 and 27,700 cytology tests which were found to have low-grade and high-grade cervical abnormalities respectively in women aged 20–69 years, and that 33,200 women with abnormal cytology had a follow-up histological evaluation. These findings are broadly consistent with the number of cytology tests with an abnormal result in 2010 (78,510 tests associated with low-grade abnormalities and 28,491 tests associated with high-grade abnormalities), and the number of cytology tests performed which were followed by a histological evaluation test in 2009 (38,859 tests) published by AIHW [5]

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Summary

Introduction

The National Cervical Screening Program in Australia currently recommends that women aged 18–69 years are screened with conventional cytology every 2 years. The National HPV Vaccination Program in Australia commenced in 2007. This comprises a school-based program, generally targeting girls in the first year of highschool (approximate age 12–13 years), and a catch-up program, running until the end of 2009, which provided vaccination for females aged between 13 and 26 years. Vaccination coverage in females aged between 18 to 26 years over the course of the catch-up program was between 30 and 38% for the full three-dose course [6]. Many of the women in the catch-up cohort were expected to have participated in the cervical screening program

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