Abstract

In 2003, the Journal of Translational Medicine was launched to foster the publication of high quality research in both "bench-to-bedside" as well as ex vivo human observation. In spite of the success of several large-scale observational studies, e.g. Framingham Heart Study, the opportunity to expand upon the ex vivo human observation has remained limited within the field of translational medicine. We believe that this presents a significant opportunity that merits consideration in both the planning and analysis of large scale observational studies and can contribute greatly to expanding our approaches in translational medicine

Highlights

  • In 2003, the Journal of Translational Medicine was launched to foster the publication of high quality research in both “bench-to-bedside” as well as ex vivo human observation

  • * Correspondence: m.liebman@strategicmedicine.com 1Strategic Medicine, Inc, 231 Deepdale Drive, Kennett Square, PA 19348, USA Full list of author information is available at the end of the article lead to potential hypotheses that foster further experiment and analysis

  • That for observational studies to be considered within Journal of Translational Medicine (JTM)’s definition of clinical practice, there are several qualities that such a study needs to address in its design and implementation and we outline these below

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Summary

Introduction

In 2003, the Journal of Translational Medicine was launched to foster the publication of high quality research in both “bench-to-bedside” as well as ex vivo human observation. * Correspondence: m.liebman@strategicmedicine.com 1Strategic Medicine, Inc, 231 Deepdale Drive, Kennett Square, PA 19348, USA Full list of author information is available at the end of the article lead to potential hypotheses that foster further experiment and analysis. They focus on establishing association, not proving cause and effect, but can be invaluable for use in the design of more conventional, controlled clinical studies.

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