Expanding DNA database effectiveness

Abstract

DNA databases effectively develop investigative leads, with database size being directly proportional to increased chances of solving crimes as demonstrated by a business case including a universal STR database example. DNA database size can be expanded physically by increasing the number and type of qualifying offenses, adding arrestees, or moving towards a universal database. The theoretical size of a DNA database can also be increased scientifically by using the inherent nature of DNA sharing by biologically related individuals by using an indirect matching strategy including Partial Matching, Familial Searching, and Investigative Genetic Genealogy (IGG). A new strategy is introduced using areas of shared DNA as a search key to locate potential relatives for further kinship evaluation. New search key strategies include Y-STR, mtDNA, and X Chromosome searching to locate potential relatives, coupled with kinship and genetic genealogical research, as well as expanded use of unidentified human remains (UHRs).