Expanded polytetrafluoroethylene-valved conduit with bulging sinuses for right ventricular outflow tract reconstruction in adults

Abstract

Generally, right ventricular outflow tract reconstruction in adults is performed using homografts or xenograft. However, sufficient graft material is difficult to obtain and has the problems of calcification and structure destruction. We, therefore, evaluated using expanded polytetrafluoroethylene- (ePTFE)-valved conduits with bulging sinuses for right ventricular outflow tract reconstruction in adults. Between February 2006 and April 2008, a total of five patients (three men, two women), ages 25-51 years old (mean +/- SD, 40 +/- 11 years)] underwent right ventricular outflow tract (RVOT) reconstruction in our institution. In three patients, RVOT reconstruction was performed with the Ross procedure; and in all cases, tricuspid ePTFE (valved conduits with bulging sinuses were used. The diameter of the conduit was determined according to the RVOT size. Valve function was followed up using echocardiography after surgery and during the early/mid-term periods of recovery (13 months to 3.0 years). No morbidity occurred, and no patient required further surgery during the follow-up period. During these follow-up periods, pulmonary observation revealed that no patients had stenosis; regurgitation was mild in one patient and trivial in four patients. In regard to the tricuspid valve, regurgitation was trivial in four patients and mild in one patient. Although long-term follow-up is required to confirm the durability of the ePTFE-valved conduit with bulging sinuses, the present results indicate a satisfactory result in patients who undergo RVOT reconstruction, even in adult cases.