Abstract
The average vertebrate gene consists of multiple small exons (average size, 137 nucleotides) separated by introns that are considerably larger(1). Thus, the vertebrate splicing machinery has the task of finding small desired exons amid much longer introns. The splice site consensus sequences that drive exon recognition are located at the very termini of introns(2, 3). Despite the discriminatory challenge faced during exon recognition in large multiexon premessenger RNAs, vertebrate splice sites are short and poorly conserved.
Highlights
Summary
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
