Existence and coexistence of calcitonin gene-related peptide, vasoactive intestinal polypeptide- and somatostatin-like immunoreactivities in spinal cord motoneurons of developing embryos and post-hatch chicks

Marcelo J Villar,Monique Huchet,Tomas Hökfelt,Jean-Pierre Changeux,Jan Fahrenkrug,John C Brown

doi:10.1016/0304-3940(88)90193-0

Existence and coexistence of calcitonin gene-related peptide, vasoactive intestinal polypeptide- and somatostatin-like immunoreactivities in spinal cord motoneurons of developing embryos and post-hatch chicks

Marcelo J Villar, Monique Huchet + Show 4 more

https://doi.org/10.1016/0304-3940(88)90193-0

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Journal: Neuroscience Letters	Publication Date: Mar 1, 1988
Citations: 51

Affiliation: Karolinska Institutet, Institut Pasteur, Bispebjerg Hospital, Medical Council of Canada, University of British Columbia

#Vasoactive Intestinal Polypeptide #Spinal Motoneurons + Show 8 more

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Abstract

By use of immunocytochemical methods, it is shown that immunoreactive calcitonin gene-related peptide (CGRP), vasoactive intestinal polypeptide (VIP) and somatostatin (SOM) are present in motoneurons in the chicken spinal cord. While CGRP-like immunoreactivity (LI) is present in numerous motoneurons both before and after hatching, SOM- and VIP-LI markedly decline at the end of the embryonic period. Evidence is also provided for coexistence of some of these peptides in certain spinal motoneurons.

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