Abstract

From Ta Ta Fund Conf Repr Ta An 80-year-old man presented with a 12-week history of a generalized pruritic skin eruption. The physical examination revealed diffuse erythema and scaling of the entire body with sparing of his face and palmoplantar surfaces (Fig 1). A tense bulla was identified on the sole of his left foot (Fig 2). Hewas otherwise well and had been taking colchicine for gout for several years. A laboratory study revealed a white blood cell count of 13,000 L, of which 25% were eosinophils. A biopsy specimen revealed a subepidermal blister containing eosinophils and lymphocytes. Direct immunofluorescence studies are shown in Fig 3 (A, immunoglobulin G; B, complement 3).

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