EXFOLIATIVE CHEILITIS: REPORT OF TWO CASES FOCUSING ON CLINICAL MANAGEMENT

Abstract

This report describes 2 cases of exfoliative cheilitis, an uncommon inflammatory condition affecting the lips, characterized by chronic production and desquamation of thick keratin scales. A 34-year-old man with psoriasis presented with a 5-year history of persistent lip desquamation, reporting unsatisfactory results from previous treatments (topical corticosteroid, 5-fluorouracil, moisturizing agents, CO₂ laser ablation). Physical examination revealed lip erythema and desquamation. Treatment with topical corticosteroid was effective and prescribed as maintenance therapy. One year later, the condition recurred and was treated with a topical formulation containing clobetasol and salicylic acid. A 33-year-old woman, reporting anxiety and a habit of lip licking, presented with continuous lip peeling, crusting, and concurrent angular cheilitis. Treatment with dexpanthenol-containing ointment and miconazole gel was successful. Five months later, lip scaling and fissures were observed and treated with topical dexpanthenol-containing ointment. Anamnesis and clinical findings were essential for exfoliative cheilitis diagnosis in both cases, which remain under follow-up.