Abstract
Our understanding of exertional rhabdomyolysis in the horse has advanced considerably over the past 10 years. Not long ago, this syndrome was considered to be a single disease entity, also known as azoturia or Monday morning disease. Now, several distinct and very different conditions that result in this common clinical presentation have been recognised. The most documented of these conditions are recurrent exertional rhabdomyolysis (RER) and polysaccharide storage myopathy (PSSM), the latter having been recently classified into type 1 and type 2 PSSM. The availability of genetic testing and widespread use of muscle biopsy sampling have facilitated clinical diagnosis of underlying myopathies in the field.
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