Abstract
This chapter provides the most relevant knowledge on the role of cardiopulmonary exercise testing (CPET) in heart failure, key methodological aspects are discussed, the importance of careful interpretation of CPET data is highlighted and areas of future work. Cardiovascular disease remains one of the biggest challenges to healthcare professionals in the United Kingdom and worldwide. Common symptoms and physical presentations of heart failure include dyspnoea, fatigue and peripheral and/or pulmonary oedema. A hallmark indicator of heart failure is also a reduced exercise capacity, indicating that heart failure is a disease of reduced oxygen availability/consumption. Valuable clinical information requires sound measurements that are precise and repeatable so that comparisons within one person over time, as well as against clinical criteria, can be made with confidence. Recent data clearly suggest that multiple biological systems are affected in patients with heart failure.
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