Exercise Mimetics: Harnessing the Therapeutic Effects of Physical Activity

Abstract

Abstract: Over the past decade, there has been an increase in both scientific and commercial interest in finding bioactive oral substances, also known as "exercise pills" or "exercise mimetics," that replicate or enhance the benefits of exercise. The benefits of an active lifestyle for both the body and brain are becoming more and more obvious. However not everyone can exercise because of illness, trauma, or age-related disease. Both artificial and natural substances stimulate genes involved in the metabolic remodelling of skeletal muscle, activate some of the major regulators, and simulate exercise. The numerous health advantages of physical activity are not being put into practice. Exercise-mimetic drugs are being developed in an attempt to bypass the necessity of physical activity for promoting health they replicate the effects of peptide molecules released by muscles that are produced when exercised. The goal is to replicate physiological reactions even in the absence of physical activity. Since physical activity is still the most effective treatment, the creation of "exercise mimetics" that target specific muscles .The review deals with the disorders that can treated with exercise mimetics