Abstract

Background:Asthma is a common illness, especially among children. Exercise-induced asthma is an important consideration, both as a factor, limiting physical activity of patients, and also as an indicator of poor long term control. We investigated pre-Valence of exercise-induced asthma in a group of asthmatic children living in southern Iran.Methods:We conducted treadmill exercise challenge test in 40 young asthmatic patients aged 6 to 18. After 8 minutes exercise to achieve 80% of maximum heart rate predicted for age, patients were examined and spirometry values recorded at frequent intervals. We defined exercise-induced asthma as 10% or more decline in Forced Expiratory Volume in one second (FEV1) within 30 minutes after exercise challenge.Results:Of 40 patients evaluated, 22 patients (55% of total) met our criteria for exercise-induced asthma. Most positive responses (7 of 22, 31.8%) occurred at about 10 minutes after exercise. Cough was the most consistent sign (18 of 22 patients, 81%). In 2 patients (9%), FEV 1 decline did not accompany any symptom or sign.Conclusion:We concluded that Exercise- induced asthma occurs in a relatively smaller subset of southern Iranian asthmatic children. Also treadmill exercise challenge performed by a trained staff, following standard protocol and using enough monitoring and precautions is safe and diagnostic in children and adolescents.

Highlights

  • Exercise-induced asthma (EIA) is defined as the condition in which exercise induces symptoms in patients who have asthma (Weiler et al, 2007)

  • We concluded that Exercise- induced asthma occurs in a relatively smaller subset of southern Iranian asthmatic children

  • In 19 of 22 patients with positive response (86.4%), Peak Expiratory Flow (PEF) decline was more than 10% and in 15 patients of 22 positive responses (68.2% ), FEF25-75 decline was more than 25%.Gender had no statistically meaningful effect on development of EIA

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Summary

Introduction

Exercise-induced asthma (EIA) is defined as the condition in which exercise induces symptoms in patients who have asthma (Weiler et al, 2007). Exercise- induced bronchoconstriction in non-asthmatic athletes is a distinct entity not considered here. An estimated 12% of the pediatric population has exercise induced bronchoconstriction and 30% of these patients may develop adult asthma (Porsbjerg et al, 2005). Few studies are available estimating EIA in Iranian asthmatic children. Exercise-induced asthma is an important consideration, both as a factor, limiting physical activity of patients, and as an indicator of poor long term control. We investigated pre-Valence of exercise-induced asthma in a group of asthmatic children living in southern Iran

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