EXERCISE EFFECTS IN PATIENT WITH MS AFTER PERCUTANEOUS MITRAL VALVULOPLASTY

Abstract

495 The purpose of this study was to evaluate stationary bicycle training effects in patients with MS after PMV. All 19 MS patients were studied. Patients were randomized to exercise group (n=8, EG) or control group (n=11, C). All patients performed exercise test four times using electrically braked bicycle ergometer with 10 watt ramp protocol; before PMV and 1 week, 1 month and 3 months after PMV. Home exercise training of EG consisted of 10 min warm-up, 20 to 25 min stationary bicycle exercise with the intensity of 50-60% peak ˙Vo2 and 5-10 min cool-down. They performed their work 3 to 5 days/week during 3 months. In both group, mitral valve area increased significantly (7±0.1 vs 1.8±0.3 cm2 in EG, 0.9±0.2 vs 1.9±0.3 cm2 in C, P<.05) and mean transmitral pressure gradient decreased significantly (13.6±7.0 vs 4.9±1.0 mmHg in EG, 12.1±6.3 vs 3.7±1.2 mmHg in C, P <.05) after PMV. Peak HR(from 165±18.1 to 171±16.8 bpm), Vd/Vt (from 0.24±4.1 to 0.19±3.2), breath reserve (from 63.8±4.1 to 55.7±5.1) were not changed in EG during 3 months. And at AT, HR (from 66.8±57.2 to 90.5±90 bpm) and ˙Vo2/kg (from 5.2±6.1 to 11.6±7.9 ml/kg/min) appeared to increase but there were no significance statistically. But compared before PMV, exercise endurance (from 510.0±105.3 to 704.8±92.9 sec, P <.05), peak workload (from 63.1±15.6 to 93.5±12.5 Watt, P<.05), peak Vo2/kg (from 17.9±2.9 to 24.7±3.3 ml/kg/min, P<.05) were higher in EG three months after PMV. But in control, no parameter [Illegible Text] changed. This results indicate that MS patients with PMV should be treated with [Illegible Text] training and exercise training also can provide positive effects on MS patients' capacity.