Abstract

Objective: This meta-analysis and systematic review examined the effects of exercise interventions on alcohol consumption and binge drinking in individuals with alcohol use disorder (AUD).Data sources: PubMed, Web of Science, Google Scholar, SPORTDiscus, and ERIC databases.Study Inclusion and Exclusion Criteria: Peer-reviewed randomized controlled trials published in English between 1970 and 2021. All studies compared exercise (Ex) and treatment as usual (TAU) to TAU in adults with an alcohol-related diagnosis. All forms of exercise interventions were included (e.g., aerobic exercise, yoga, resistance exercise, etc.).Data Extraction: Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols standard and the Meta-Analyses and Systematic Reviews of Observational Studies guidelines were followed. Risk of bias was assessed using the Cochrane risk-of-bias tool as described by the Cochrane Handbook for Systematic Reviews and Interventions.Results: The literature searches retrieved a combined 2527 studies, with 1,034 studies screened after removal of duplicates and 973 (94%) rejected after reviewing titles and abstracts. Full-text review was performed on 61 studies, with seven studies meeting inclusion criteria for qualitative and meta-analysis. Across seven studies (n = 492 participants), a significant effect (Z-value = −3.37; g = −0.30; 95% CI [−0.50—−0.09]; p = 0.001) was found for Ex+TAU on drinking volume. There was no effect of Ex+TAU on binge drinking. The effect of Ex+TAU on physical fitness (VO2max, ml•kg−1•min−1) was significant (Z-score = 3.70; g = 0.64; 95% CI [0.19–1.08]; p < 0.001).Conclusions: Exercise interventions may decrease alcohol consumption and improve fitness and can be an effective adjunctive treatment for individuals with alcohol-related diagnoses including AUD.

Highlights

  • Alcohol use disorder (AUD) is a chronic condition affecting nearly 283 million people aged 15 years and older worldwide and 14.4 million adults ages 18 years and older in the United States (World Health Organization, 2010; National Institute on Alcohol Abuse Alcoholism, 2017)

  • Across seven studies (n = 492 participants), a significant effect (Z-value = −3.37; g = −0.30; 95% confidence intervals (95% CIs) [−0.50—−0.09]; p = 0.001) was found for Ex+treatment as usual (TAU) on drinking volume

  • There was no effect of exercise and treatment as usual (Ex+TAU) on binge drinking

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Summary

Introduction

Alcohol use disorder (AUD) is a chronic condition affecting nearly 283 million people aged 15 years and older worldwide and 14.4 million adults ages 18 years and older in the United States (World Health Organization, 2010; National Institute on Alcohol Abuse Alcoholism, 2017). The Diagnostic and Statistical Manual—Version 5 (DSM-5) defines AUD as a problematic pattern of alcohol use leading to clinically significant impairment or distress (American Psychiatric Association, 2013). The DSM-5 further describes AUD as a cluster of behavioral and physical symptoms that can include withdrawal, tolerance, and craving, which can lead to both alcohol abuse and dependence (American Psychiatric Association, 2013). Binge drinking is the most common, costly, and deadly pattern of alcohol use in the United States (Centers of Disease Control and Prevention, 2020).

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