Abstract
BackgroundAlthough many post-participation outcomes in different types of physical training (e.g., aerobic and strength) have been previously investigated for the treatment of polycystic ovary syndrome, there is no recent systematic review of the relationship between various types of intervention and the reproductive function of women with PCOS. The current paper describes a systematic review protocol on the benefits of physical exercise and dietary or drug interventions on endocrinological outcomes in women with PCOS.MethodsPubMed/MEDLINE, Science Direct, Bireme, Scopus, Web of Science, ProQuest, Cochrane Library (Cochrane Systematic Reviews Database, Cochrane Central Register of Controlled Studies (CENTRAL) databases will be searched. Studies randomized controlled trials reporting on intervening changes in exercise interventions with or without interventions compared such as diet, medication and acupuncture on the menstrual cycle, and fertility in women with PCOS will be included. Results will be on the decrease of the characteristics of hyperandrogenism, insulin resistance, and obesity. Studies published since 2010 and in the English language will be included.DiscussionThis systematic review will identify improvement strategies and types of interventions that are geared toward improving endocrine and consequently metabolic parameters. Thus, the use of such strategies may increase the types of low-cost non-drug therapies that aid in the treatment of PCOS.Systematic review registrationPROSPERO CRD42017058869
Highlights
Many post-participation outcomes in different types of physical training have been previously investigated for the treatment of polycystic ovary syndrome, there is no recent systematic review of the relationship between various types of intervention and the reproductive function of women with Polycystic ovarian syndrome (PCOS)
Polycystic ovarian syndrome (PCOS) is an endocrinopathy that affects women of reproductive age, whose main clinical features include menstrual dysfunction, infertility, clinical, and biochemical hyperandrogenism [1, 2]. Since these characteristics are the main concerns of patients with PCOS, and several therapeutic strategies are used in attempts to improve ovulatory function, several studies have shown that body weight loss can restore menstrual cycle and ovulation in PCOS women, an
Lifestyle modification including exercise and diet has been recommended as the first-line therapy for women with PCOS, since this practice would reduce insulin resistance, improving metabolism and reproductive function [6, 7]
Summary
PubMed/MEDLINE, Science Direct, Bireme, Scopus, Web of Science, ProQuest, Cochrane Library (Cochrane Systematic Reviews Database, Cochrane Central Register of Controlled Studies (CENTRAL) databases will be searched. Studies randomized controlled trials reporting on intervening changes in exercise interventions with or without interventions compared such as diet, medication and acupuncture on the menstrual cycle, and fertility in women with PCOS will be included. Results will be on the decrease of the characteristics of hyperandrogenism, insulin resistance, and obesity. Studies published since 2010 and in the English language will be included
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