Abstract
Exemestane-Induced Eosinophilic Colitis in a Patient with Grade 3 Ductal Carcinoma In-Situ: A Case Report and Review of the Literature
Highlights
Exemestane is an irreversible, steroidal aromatase in-activator that structurally resembles androstenedione [1]
Exemestane was deemed the probable cause of the acute episode of eosinophilic colitis in this case
One other prior case with aromatase inhibitor-induced eosinophilic colitis has been reported with letrozole, this is the first case report of eosinophilic colitis associated with exemestane
Summary
Attention to the possibility of colitis is required when a patient is on a new medication in the setting of worsening or new onset watery diarrhea. It is important to report these cases and closely monitor those who develop gastrointestinal symptoms while on aromatase inhibitors since these drugs are widely used and are the mainstay of therapy in patients with estrogen receptor positive breast cancer
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
