Executives functions in co-occuring adult attention deficit hyperactivity disorder and alcohol use disorder

A D’Alessandro,P Bendimerad

doi:10.1192/j.eurpsy.2021.652

Abstract

IntroductionExecutives functions (EF) are cognitive processes mediating the ability to successfully regulate thoughts and behaviours in order to fulfil a goal. EF impairment has been found both in the Attention Deficit Hyperactivity Disorder (ADHD) and in the Alcohol Use Disorder (AUD). Deficits in EF may have a major impact on patients’ everyday life.ObjectivesThe aim of this study was to evaluate EF in a population with a dual diagnosis of Adult ADHD et AUD. We also evaluated the correlation between EF and the dimensions of quality of life.MethodsFor this observational multicentric study, we included patients with AUD starting long-term residential treatment. We used ASRS v.1.1 to screen for Adult ADHD and DIVA to confirm the diagnosis. We assess EF with BRIEF-A. WHOQoL-BREF was used to evaluate quality of life.Results Our population consists of 49 patients. Adult ADHD prevalence was 24,49%. Impairment score of all EF explored (Inhibition, Shifting, Emotional Control, Self-Monitoring, Initiative, Working Memory, Planning/Organizing, Organization of materials, Task Monitoring) was higher in patients with co-occuring Adult ADHD and AUD than in patients without Adult ADHD (p<0,001). We found strong negative correlation between Psychological Health and impairment score of Inhibition (p<0,001), Emotion Control (p<0,001), Self-Monitoring (p<0,001) and planning/Organizing (p<0,001). The other dimensions of quality of life were poorly correlated to EF impairment.ConclusionsThe prevalence of Adult ADHD in AUD patients is high. When AUD and Adult ADHD coexist, EF impairment is stronger and quality of life is poorer. Psychological health and EF impairment are strongly associated.

Highlights

In Russia, the prevalence of GERD is 18-46% [Ivashkin V
GERD leads to a significant decrease in the quality of life of patients, especially with nocturnal symptoms, extraesophageal symptoms, and increases the risk of complications such as bleeding from ulcers and erosions, peptic strictures and, which causes the greatest caution, Barrett’s esophagus and esophageal adenocarcinomas Objectives: The medical and social significance of the pathology of the thyroid gland and gastrointestinal tract problem is determined by their high prevalence regardless of age, the annual increase in morbidity and the decrease in the quality of life (QOL)
Patients were divided in two groups: patients with GERD; patients with GERD and hypothyroidism

Summary

European Psychiatry

S243 treatment and improve patient’s quality of life. The publication was prepared with the support of the “RUDN University Program 5-100”. Psychiatry And Medical Psychology, RUDN University, Moscow, Russian Federation *Corresponding author.

Introduction

Objectives

Findings