Executive summary of the Consensus Document of the Transplant Infection Study Group (GESITRA) of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) and the National Transplant Organization (ONT) on the Selection Criteria of Donors of Solid Organs in relation to Infectious Diseases

Óscar Len ,Asunción Moreno,Marta Bodro,José Luis Pérez-Sáenz,Marino Blanes,Jordi Carratalà,Carlos Lumbreras,José María Aguado,Elisa Cordero,Elisa Vidal,Joan Gavaldà,María Carmen Fariñas,Francesca Norman ,Beatriz Mahíllo ,Mario Fernández‐Ruiz ,José Miguel Montejo ,Jesús Fortün ,Rafael San Juan ,Patricia Muñóz ,Pilar Martín‐Dávila ,Tomás Pumarola ,Francisco López‐Medrano ,Ibai Los‐Arcos ,Rogelio López‐Vélez ,N Sabé ,María Ángeles Marcos ,Beatriz Domínguez‐Gil

doi:10.1016/j.eimce.2019.10.014

Abstract

The immunosuppressive treatment that recipients receive from a solid organ transplantation hinders the defensive response to infection. Its transmission from the donor can cause dysfunction or loss of the graft and even death of the recipient if proper preventive measures are not established. This potential risk should be thoroughly evaluated to minimise the risk of infection transmission from donor to recipient, especially with organ transplantation from donors with infections, without increasing graft dysfunction and morbidity and mortality in the recipient. This document aims to review current knowledge about infection screening in potential donors and offer clinical and microbiological recommendations about the use of organs from donors with infection based on available scientific evidence.

Full Text