Abstract

The presence of excessive left ventricular (LV) trabeculation remains enigmatic: both seen on imaging in congenital, inherited, and acquired cardiomyopathies and in normal, healthy individuals with no apparent cardiovascular abnormalities. Understanding the clinical implications of LV trabeculation in various cardiomyopathies may help in personalizing therapeutic options and defining prognoses. Increased Left Ventricular Trabeculation Is Associated With Increased B-Type Natriuretic Peptide Levels and Impaired Outcomes in Nonischemic CardiomyopathyCanadian Journal of CardiologyVol. 36Issue 4PreviewThe clinical significance of left ventricular (LV) trabeculation remains unknown in cardiomyopathies. B-Type natriuretic peptide (BNP) strongly reflects LV end-diastolic wall stress and is a useful prognostic marker of cardiovascular diseases. The enhanced identification of LV trabeculae (T) with the use of cardiac magnetic resonance and the evaluation of its relationship with BNP may elucidate the biologic significance and clinical impact of trabeculation in patients with nonischemic cardiomyopathy (NICM). Full-Text PDF

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