Excessive Collapsibility of Bronchi in Bronchiectasis

Abstract

To evaluate the frequency and severity of bronchomalacia, defined as excessive collapsibility of bronchi, in bronchiectasis; to compare the extent of air trapping in bronchiectasis patients with/without bronchomalacia; and to correlate the severity of bronchomalacia and the extent of air trapping versus pulmonary function. Forty-six patients with bronchiectasis evaluated by volumetric expiratory high-resolution computed tomography (CT) and pulmonary function tests were studied. The presence and severity of bronchomalacia were evaluated on contiguous axial high-resolution CT images using a 4-point scale. The extent of air trapping was graded on coronal reformations using a 5-point scale. Differences in the extent of air trapping in patients with/without bronchomalacia and the correlation between the severity of bronchomalacia and the extent of air trapping were investigated. The severity of bronchomalacia and the extent of air trapping were correlated with pulmonary function. Of 46 patients with bronchiectasis, 32 patients (70%) had bronchomalacia. Air trapping was present in 43 patients (93%). The extent of air trapping in patients with bronchomalacia was significantly greater compared with the patients without bronchomalacia (P=0.0308). The correlation between the severity of bronchomalacia and extent of air trapping was not statistically significant (rs=0.029, P=0.8457). The extent of air trapping in bronchiectasis patients with bronchomalacia was significantly greater compared with bronchiectasis patients without bronchomalacia, suggesting that the bronchomalacia is one of the underlying mechanisms of air trapping in bronchiectasis.