Abstract
AbstractPapillon–Lefèvre syndrome (PLS) is a rare autosomal recessive disease that presents clinically with palmoplantar keratoderma and periodontitis and results in early‐onset dental loss. PLS management is difficult. We report a 30‐year‐old female with PLS who had unfavourable response to topical keratolytic creams, oral isotretinoin and narrow‐band ultraviolet‐B (NB‐UVB) phototherapy but showed significant clinical improvement to adalimumab.
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