Abstract
AbstractRadiotherapy (RT) has been a long-standing treatment option for low-grade glioma. Improvements in tumor control and reduced radiation-related toxicity can be attributed to advances in neuroimaging as well as RT treatment planning and delivery techniques. The molecular markers such as isocitrate dehydrogenase and lpl9q play a key role in determining which patients will benefit most from combined radiation and systemic therapy. We hereby report two cases of favorable molecular low-intermediate grade oligodendroglioma treated with modern proton pencil-beam therapy under high-precision image guidance showing excellent radiological response that is usually not seen with conventional photon radiation.
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