Examples of application perfusion pulmonary scintigraphy in assessing treatment efficacy artery pulmonary embolism

Abstract

ABSTRACT. Background. The significance of the problem of pulmonary embolism is currently determined by an increase in the incidence of various diseases, postoperative and post-traumatic embolisms in complicated surgical interventions, the circumstances that the pulmonary embolism is the third most common cause of death in developed countries, yielding only cardiovascular disease and malignant neoplasms. Methods. The results of the dynamic observation of the treatment of pulmonary embolism in 20 patients who were on inpatient treatment in Mechnikov Dnipropetrovsk Regional Hospital. Studies were conducted in the period of 4-9 days. As a result of dynamic observation in 6 patients, the course of treatment was considered positive and no correction of treatment was performed. In 9 patients, there was a slight positive dynamics of the state of perfusion of pulmonary tissue and they were given a correction of therapeutic treatment - an increase in the dose of thrombolytic drugs. In 5 patients, the disease was considered unfavorable - an increase in the number and area of lesions was detected, therefore, patients were given surgical intervention to eliminate thrombotic masses from the pulmonary artery system. Results. Based on the results of our observations, it has been established that the use of perfusion pulmoscinigraphy makes it possible to study perfusion of the lungs, to determine their anatomo-topographic state and the amount of functioning parenchyma. With its help, it is possible to detect minimal metabolic disturbances in the lungs. Conclusion. Perfusion pulmonary scintigraphy in connection with sufficient informativeness, low invasiveness and relatively low radiation load, can be used inUkraine as a method of dynamic observation of PE treatment.