Abstract
To the Editor: Biologics are highly efficacious biologic for treating moderate-to-severe plaque psoriasis, particularly brodalumab.1 However, the use of brodalumab has been severely limited due to a black box warning and an associated Risk Evaluation and Mitigation Strategies program indicating a possible increased risk of suicidality. This warning was applied due to 4 possible suicides during phase III clinical trials, of which only 3 were verified. Closer examination of these cases shows that all 3 had significant life stressors and no chronological relationship between drug administration and suicide was present.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.