Examining the influence of the cerebral cortex in range of motion exercise using MEG

Abstract

In rehabilitating stroke patients, many therapists use range of motion exercise (ROM-ex) at early post onset. There are three general types of ROM-ex: passive, active, and active-assistive ROM-ex is used to prevent joint contracture in paralyzed limbs and to assist in recovery of the central nervous system (CNS). However, its effect on CNS recovery is unclear. Therefore, this study compared the influence of different tasks, including passive and active ROM-ex and imagined extension/flexion at the elbow, on the cerebral cortex. The subjects were six healthy volunteers. We used a magnetoencephalogram (MEG) to measure cerebral cortex activity. In the active ROM-ex task, we confirmed a dipole in the motor area in all subjects. It has been suggested that this dipole is activity of the motor-related field (MRF). By contrast, in the passive ROM-ex experiment, we did not confirm a dipole in the cortex. In addition, in the experiment with no joint motion, in which the subject only imagined moving the elbow joint from flexion to extension, it was possible to estimate a dipole in the motor area. Therefore, an imaginary task might be a possible method of activation when voluntary movement is impossible.