Abstract
The transient evolution of granules was studied to learn new details about the underlying mechanism for continuous wet granulation in a twin-screw extruder. Sieving and a new inline PAT for particle size development was used to gain these insights. The onset for steady state was established based on observing a consistent PSD, which occurred at five times the mean residence time of the process, over a range of degrees of fill (DF; 12–30 %). The early stages of startup for granulation were captured by the inline PAT, showing different stages of granule growth for particle sizes ranging from 102 to 2230 μm. The analysis found that conveying elements have a stronger influence on granule growth at a low DF whereas the kneading zone had a stronger influence on granule growth at a higher DF. This study presents new details on this black-box process while highlighting the unique value of PAT to twin-screw granulation.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
