Abstract
Distortion product otoacoustic emissions (DPOAEs) are sounds measured in the ear canal in response to a two-tone stimulus. Because DPOAEs are measured non-invasively, they have been intensively studied and widely applied for the clinical assessment of hearing function. In this work, we combine a three-dimensional computational model with mechanical-electrical-acoustic coupling with in vivo measurements of the pressure in scala tympani and the extracellular electrical outer hair cells (OHCs) response to study distortion product (DP) generation by OHCs in the gerbil cochlea. An efficiency non-linear frequency domain algorithm is used to simulation the nonlinear response of the cochlea in response to a two-tone stimulus. The influence of primary frequency ratio (on IDP generation and propagation is examined. The results show the IDPs are broadly generated by OHCs but their contribution to OAEs are spatially restricted. This work not only improves our understanding of the role of the OHC electromotility in DP generation, but will also benefit clinical noninvasive hearing assessment based on otoacoustic emissions.
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