Abstract
<div class="section"><div class="section"><div class="layoutArea"><div class="column"><p><span>Clinical and research reports evidence cases of failed endodontic treatment complaining bacterial resistance to conventional therapeutic protocols. Thus, the use of an alternative intracanal medication covering a broader microbial spectrum in order to increase the success rate of endodontic treatment is necessary. In the present study the bacterial colonization of </span><span>Enterococcus faecalis </span><span>(ATCC 29212), </span><span>Porphyromonas gingivalis </span><span>(ATCC 33277), </span><span>Actinomyces odontolyticus </span><span>(ATCC 17929) and </span><span>Prevotella bucae </span><span>(LIBA-6229) on dentin specimens and in an </span><span>ex vivo </span><span>model simulating human root canal infection was demonstrated. Our study evaluated the antimicrobial effectiveness of two poliantibiotic pastes </span>(amoxicillin with clavulanic acid-ciprofloxacin and metronidazole-amoxicillin-ciprofloxacin), and calcium hydroxide dressing. Both antibiotic intracanal dressings were equally effective for bacteria eradication, however in both research models, poliantibiotic pastes reveal higher antimicrobial effectiveness than calcium hydroxide. </p></div></div></div></div>
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