Evolutionary synthesis of almost closed conservational processes

Abstract

Publisher Summary This chapter discusses the synthesis of a hypothetical metabolic model that follows the pattern of the citrate cycle (Szentgyorgyi–Krebs cycle). This class of problems is characterized by the possible, alternative biochemical pathways, accompanied with incomplete, uncertain knowledge about the important parameters. The model is recognized and identified by a generic simulator collaborating with a genetic algorithm. The investigated problem is isomorphic with many synthesis tasks, where good solutions have to be selected from among the possible, alterative production routes, considering the prescribed rates of the input and output flows between the given system and the environment. The behavior of the natural systems and the notion of the Almost Closed Conservational Processes (ACCP) are also introduced in the chapter. The conscious design and control of the ACCP is fundamental in the future engineering, because the global natural system is an ACCP, with the solar energy as the single environmental input. The large scale and long-term character of ACCP synthesis needs new methodologies and the reconsideration of the existing goal functions.