Abstract
It is no doubt quite difficult to solve the riddle of the origin of life. So, firstly, I would like to point out the kinds of obstacles there are in solving this riddle and how we should tackle these difficult problems, reviewing the studies that have been conducted so far. After that, I will propose that the consecutive evolutionary steps in a timeline can be rationally deduced by using a common event as a juncture, which is obtained by two counter-directional approaches: one is the bottom-up approach through which many researchers have studied the origin of life, and the other is the top-down approach, through which I established the [GADV]-protein world hypothesis or GADV hypothesis on the origin of life starting from a study on the formation of entirely new genes in extant microorganisms. Last, I will describe the probable evolutionary process from the formation of Earth to the emergence of life, which was deduced by using a common event—the establishment of the first genetic code encoding [GADV]-amino acids—as a juncture for the results obtained from the two approaches.
Highlights
In order to solve the riddle on the origin of life, it is important to understand the process by which the fundamental life system was formed, which is composed of three major elements: genes, genetic code, and proteins
The bottom-up approach is surely a general way for studying the origin of life, but it is incapable of solving this problem alone, principally because it is not able to elucidate the formation process of the fundamental life system composed of genes, genetic code, and proteins
Researchers have tried to understand, using the bottom-up approach, how the first life emerged on the primitive Earth, but it has been so far proven impossible to solve the riddle of the origin of life
Summary
In order to solve the riddle on the origin of life, it is important to understand the process by which the fundamental life system was formed, which is composed of three major elements: genes, genetic code, and proteins. Orderthe to standpoint reinforce the of RNA by hypothesizing that the researchers earliest have predecessor started to search for new ways to solve the riddle of the origin of life, especially in recent of the nucleic acids was a β-linked polyester made from malic acid [5]. It must be impossible to solve the catalytic peptides and/or proteins as their aggregates Iriddle consent to their ideas because it is important to suppose stable predecessor of theory, RNA or to of the origin of life even using both the co-evolution theory aand the metabolism-early stabilize fragile with peptides, especially in the watery circumstances on the primitive.
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